Advances in the Understanding of Gluten related Pathology and the Evolution of Gluten-Free Foods
This book will give you up-to-date information on the basic and clinical aspects of gluten-related disorders, the evolution of grains, bread and gluten-free products covering the necessary integration of the different fields which until recently were considered separate.
To achieve a common platform, this book has three sections.
- The first section deals with chapters explaining the immune response to the toxic peptides of gluten as well as new approaches in treatment.
- The second section revises the advances made in the clinical spectrum of the gluten-related disorders.
- The third section explores the evolution of gluten, bread products and the great challenge to elaborate gluten-free products of high quality. The technological improvements in this field will produce gluten-free foods, less expensive than at present available in food stores.
The authors are recognized investigators, active in the field of gluten-related disorders and the evolution of gluten-free products. The information provided is essential for celiacs, non-celiac gluten- sensitive persons, Patient Associations of gluten-related disorders, physicians and the food industry. It will be of help to clinical and research scientists in clinical medicine, immunology and pathology, to professionals in nutrition and gluten-free products, to the regulatory authorities, to food chemists and their technologists.
Chapters
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General preface and acknowledgments
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Epidemiology of Celiac Disease and Non-Celiac Gluten-Related Disorders
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Section IGenetics, genomics, immunology and application to therapy
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1. Genetics of Celiac Disease: HLA and non-HLA genes
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2. Mechanisms of Intestinal Tolerance to Dietary Proteins
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3. Cereal Proteins: Immunostimulatory and Toxic Peptides
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4. Pathogenesis of Celiac Disease
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5. Intestinal Microbiota and Celiac Disease
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6. Celiac Treatments, Adjuvant Therapies and Alternatives to the Gluten-Free Diet
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Section IIDiagnosis, serology, pathology and clinical entities and syndromes
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7. New Tools for the Diagnosis of Celiac Disease
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8. Intestinal Biopsy in the Diagnosis of Celiac Disease: Is it still the Gold Standard?
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9. Clinical Manifestations of Celiac Disease and Diagnostic Criteria: Differences among Children, Adolescents and Adults
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10. Extraintestinal Manifestations of Celiac Disease and Associated Disorders
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11. Follow-up of CD Patient: Is Mucosal Recovery a Goal of Therapy?
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12. Quality of Life and Psychological Distress in the Patient with CD
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13. Non-Celiac Gluten Sensitivity
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14. Wheat as an allergen: Baker's asthma, food and wheat pollen allergy
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Section III
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15. Cereals Taxonomy: The Role of Domestication and Breeding on Gluten Intolerance
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16. Analytical Tools for Gluten Detection: Policies and Regulation
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17. Gluten-Free Bakery Products and Pasta
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18. Gluten-Free Autochthonous Foodstuff (South America and other countries)
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19. Gluten-Free Spirits and Drinks
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20. Market and Nutrition Issues of Gluten-Free Foodstuff